Suchergebnisse

Introduction -- Theoretical framework and methodology -- Discursive control of natural disaster reporting in Chinese media: a historic overview -- Chinese media representation of the 2008 Wenchuan Earthquake -- Articulating Chinese national identity in the 2008 Wenchuan Earthquake Coverage -- Discourse of resistance: the global implication -- Conclusion

As an important intermediary in preschool children's play activities, outdoor sports facilities are the most effective tools to assist children in the field of perception, attention, memory and thinking. By introducing game theory and combining children's psychology and game characteristics, this article summarizes experiential, interactive and diversified designs and guiding the design concepts based on game theory, providing new design ideas and directions for the development of domestic related industries.

New Year paintings, or nianhua, created in Liangping with the use of the technique of woodblock printing, represent folk art that weaves together distinct local features, aesthetic perception and technical mastery of the artists. One of the key nianhua themes is the imagery of "Men Shen", or door gods, that banish the evil and guard doors and gates. The article discusses the imagery of door gods in Liangping nianhua printed from woodblocks.

Intro -- TITLE PAGE -- COPYRIGHT PAGE -- BRIEF CONTENTS -- DETAILED CONTENTS -- PREFACE -- ACKNOWLEDGMENTS -- ABOUT THE EDITORS -- ABOUT THE CONTRIBUTORS -- CHAPTER 1 - INTRODUCTION -- CHAPTER 2 - DIGITAL TRANSFORMATION OF TRADITIONAL CULTURAL AND CREATIVE INDUSTRY -- CHAPTER 3 - DIGITAL TRANSFORMATION OF SPATIAL EXPERIENCE IN THE CULTURAL AND CREATIVE INDUSTRY : FROM ENTERTAINMENT TO CO-CREATION -- CHAPTER 4 - NEW DIGITAL CREATIVE INDUSTRY : EMERGING DIGITAL CONSUMPTION EXPERIENCES IN THE CULTURAL AND CREATIVE SECTORS -- CHAPTER 5 - UNLOCKING NEW VALUE WITH EMERGING TECHNOLOGIES IN THE CULTURAL AND CREATIVE INDUSTRY : THE ROLE OF BLOCKCHAIN TECHNOLOGY -- CHAPTER 6 - DIGITAL CREATIVE ENTREPRENEURSHIP -- CHAPTER 7 - COPYRIGHT AND INTELLECTUAL PROPERTY MANAGEMENT IN THE DIGITAL CULTURAL AND CREATIVE INDUSTRY -- CHAPTER 8 - GLOBALIZATION AND GLOCALIZATION OF THE CULTURAL AND CREATIVE INDUSTRY IN THE DIGITAL ERA -- CHAPTER 9 - CASE STUDIES -- CHAPTER 10 - PUTTING IDEAS INTO PRACTICE -- BIBLIOGRAPHY -- INDEX.

Although many countries around the world, especially China, highlight the strategy of green development, there has been little research evaluating the effectiveness of green development policies in local area. This study explores 16 policy texts with the theme of green development in the Yangtze River Economic Belt in China. Using the Policy Modeling Consistency Index (PMC-Index) model, the paper establishes a multi-input–output policy table and scientifically and systematically evaluates these policies. The results show that the average PMC index of the 16 policy texts is 6.83, indicating a high overall quality of policy texts. The index identifies two states of policy effectiveness as being good and excellent; 50% of the total texts fall into these categories and do not fall into the category of having a low level of policy effectiveness. Five indicators, including policy timeliness, social benefits, policy audience scope, and incentives and constraints, significantly impact the PMC-Index of the policy. Six representative policy samples were selected and analyzed. The advantages and disadvantages of the policy can be more fully understood by the degree of depression of the PMC's three-dimensional curved surface (PMC-Surface) model. Finally, the paper provides theoretical recommendations for the optimization of the green development policies.

Bo Xie, Liyue Sun, Yanjun Cheng, Juan Zhou, Jihua Zheng, Weimin Zhang Department of Oncology, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou, Guangdong, People's Republic of China Introduction: There is still lack of specific biomarkers in predicting the radiosensitivity of non-small cell lung cancer (NSCLC) patients in clinic. Previous studies have shown that the EGFR gene status may correlate with radiosensitivity of NSCLC. However, the underlying mechanisms remain unknown. The aim of this study was to further investigate the correlation between EGFR mutation status and the NSCLC cell radiosensitivity and to explore the possible cellular mechanism. Methods: Eight NSCLC cell lines with different EGFR gene status were irradiated by linear accelerator, and the radiosensitivity between the cell lines was compared by cell colony formation assay and cell proliferation assay. Cell cycle and apoptosis were analysed by flow cytometry. Radiosensitivity-related protein expression was detected by Western blotting.Results: In the present study, we found that NSCLC cell lines with the epidermal growth factor receptor (EGFR) gene mutations were more sensitive to X-ray irradiation than those with wild-type EGFR (P<0.05). No difference in radiosensitivity was observed between NSCLC cells with EGFR exon19 deletion (Del 19) mutation and exon 21 point mutation at position 858 (L858R) with or without T790M mutation (P<0.05), as well as between NSCLC cells with EGFR mutation and those with acquired EGFR-tyrosine kinase inhibitors (TKIs) resistance. Mechanistically, EGFR mutations promoted NSCLC cell apoptosis in response to X-ray irradiation through the upregulation of proapoptotic protein Bax and downregulation of anti-apoptotic proteins such as Bcl-2 and DNA-dependent protein kinase catalytic subunit. In addition, phosphorylated histone (γ-H2AX) foci assay showed that EGFR mutations sustained irradiation-induced DNA damage. Conclusion: Taken together, our study demonstrates that EGFR mutations are closely associated with the increased sensitivity of NSCLC cell lines to X-ray irradiation and that EGFR mutation status is a potentially useful indicator to evaluate the effectiveness of radiotherapy in the treatment of NSCLC. Keywords: non-small-cell lung cancer, epidermal growth factor receptor, mutation, radiosensitivityErratum for this paper has been published

Xie B, Sun LY, Cheng YJ, et al. Cancer Manag Res. 2018;10;3551–3560.On page 3551, the affiliation section should be changed from: Bo XieLiyue SunYanjun ChengJuan ZhouJihua ZhengWeimin ZhangDepartment of Oncology, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou, Guangdong, People's Republic of ChinaTo: Bo Xie*Liyue Sun*Yanjun ChengJuan ZhouJihua ZhengWeimin ZhangDepartment of Oncology, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou, Guangdong, People's Republic of China*These authors contributed equally to this work.Read the original article